Veterinary Medicine International

Research Article

A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis

Table 1

Isolation of M. bovis from a range of tissues taken from 4 ferrets infected with CFU and examined postmortem at 8 weeks post infection.
Tag number432481523564
TissueLS1QL2QN3LSQLQNLSQLQNLSQLQN
Submandibular LN0−−0−−0−−0+24.3
Retropharyngeal LN0−−NS4NSNSNSNSNS0+31.7
Mesenteric LN0+1.940+16.30−32.81+1080
Upper left lung0−−0+2.960−−0+36.8
Lower left lung0+−0+−0−74.40+14.9
Upper right lung0+5.40+−0−−0+−
Lower right lung0+−0+320−81.80+−
Lung associated LN0+−0+11.82−11901+46.6
Kidney0−−0−−0−−00152
Liver0−880+−0−−0+−
Spleen0+−0−−0−−0+8.5
Kidney (2)0−−NSNSNSNSNSNSNSNSNS
1LS: lesion score.
2QL: qualitative bacteriology.
3QN: quantitative bacteriology (×102 CFU/g).
4NS: not sampled.