Research Article
A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis
Table 3
Isolation of
M. bovis from a range of tissues taken from 4 ferrets infected with
CFU and examined postmortem at 20 weeks post infection.
| | Tag number | 262 | 456 | 940 | 78968 | | Tissue | LS1 | QL2 | QN3 | LS | QL | QN | LS | QL | QN | LS | QL | QN |
| | Submandibular LN | 0 | − | − | 0 | − | 2.1 | 0 | − | − | 0 | − | − | | Retropharyngeal LN | NS4 | NS | NS | NS | NS | NS | NS | NS | NS | NS | NS | NS | | Mesenteric LN | 1 | + | 25.7 | 0 | + | | 0 | + | 70 | 0 | + | 7.0 | | Upper left lung | 2 | + | − | 0 | − | 417 | 0 | − | − | 0 | − | − | | Lower left lung | 2 | + | − | 0 | − | − | 0 | − | − | 0 | − | − | | Upper right lung | 0 | − | − | 0 | − | − | 0 | − | − | 0 | − | − | | Lower right lung | 0 | − | − | 0 | − | − | 0 | − | − | 0 | − | − | | Lung associated LN | 0 | + | 62.5 | 0 | + | − | 0 | − | − | 0 | + | 80.6 | | Kidney | 0 | − | − | 0 | − | − | 0 | − | − | 0 | − | − | | Liver | 0 | + | − | 0 | + | − | 0 | − | − | 0 | − | − | | Spleen | 0 | + | 0.78 | 0 | + | − | 0 | − | − | 0 | + | − |
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1LS: lesion score.
2QL: qualitative bacteriology.
3QN: quantitative bacteriology (×102 CFU/g).
4NS: not sampled.
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