Research Article

Effects of High-Mobility Group A Protein Application on Canine Adipose-Derived Mesenchymal Stem Cells In Vitro

Figure 2

Proliferation test of cASCs stimulated with HMGA proteins. Absorbance values were normalized to 100% in the negative control condition, significance levels are given for comparisons versus negative control condition. HMGA1 at all used levels has significant suppressive effects on cell proliferation . In contrast, cell proliferation in the HMGA2-treated groups resulted in no significant differences in comparison to the control group at all chosen concentrations. The combined protein application of 100 ng and 200 ng/mL shows a significant suppressive effect on cASCs proliferation . For statistical comparisons a one-way analysis of variance and a Tukey posttest was carried out (significance levels: * ; ** ; *** ).
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