Genetic Association Analysis of Paratuberculosis Forms in Holstein-Friesian Cattle
Table 3
Association results from apparently free versus patent PTB logistic regression analysis.
Gene
SNP
Model
Genotypes
Percentage of apparently free
Percentage of patent PTB
P
NOD2
rs43710290
Codominant
C/C; T/C; T/T
73.8; 24.1; 2.1
61.3; 38.7; 0.0
0.0179
Dominant
C/C; T/C-T/T
73.8; 26.2
61.3; 38.7
0.0345
Overdominant
C/C-T/T; T/C
75.9; 24.1
61.3; 38.7
0.0135
SP110
rs136859213
Dominant
C/C; C/T-T/T
86.6; 13.4
96.7; 3.3
0.0344
Log-additive
0, 1, 2
84.6
15.4
0.0305
rs110480812
Recessive
A/A-A/G; G/G
91.4; 8.6
82.3; 17.7
0.0467
All models were adjusted for age at slaughter (years). SNPs and genetic models with a nominal P value are only shown. No significant associations. Threshold of significance for genetic models (after permutation procedure): ; ; ; ; .
