Genetic Association Analysis of Paratuberculosis Forms in Holstein-Friesian Cattle
Table 4
Association results from latent PTB versus patent PTB logistic regression analysis.
Gene
SNP
Model
Genotypes
Percentage of latent PTB
Percentage of patent PTB
P
SLC11A1
rs109453173
Overdominant
C/C-G/G; C/G
60.4; 39.6
73.8; 26.2
0.0399
SP110
rs136859213
Dominant
C/C; C/T-T/T
84.5; 15.5
96.7; 3.3
0.0237
Overdominant
C/C-T/T; C/T
85.3; 14.7
96.7; 3.3
0.0341
Log-additive
0, 1, 2
79.2
20.8
0.0215
rs110480812
Codominant
A/A; A/G; G/G
45.9; 48.9; 5.2
45.2; 37.1; 17.7
0.0448
Recessive
A/A-A/G; G/G
94.8; 5.2
82.3; 17.7
0.0233
TLR2
rs109971269
Dominant
T/T; C/T-C/C
79.8; 20.2
69.4; 30.6
0.0194
Overdominant
T/T-C/C; C/T
81.1; 18.9
71.0; 29.0
0.0171
Log-additive
0, 1, 2
79.0
21.0
0.0357
All models were adjusted for age at slaughter (years). SNPs and genetic models with a nominal P value are only shown. No significant associations. Threshold of significance for genetic models (after permutation procedure): ; ; ; ; .
