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Veterinary Medicine International
Volume 2014, Article ID 675172, 8 pages
http://dx.doi.org/10.1155/2014/675172
Research Article

Pamidronate Disodium for Palliative Therapy of Feline Bone-Invasive Tumors

1University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA
2Advanced Veterinary Care Center, Lawndale, CA 90260, USA

Received 4 February 2014; Accepted 17 April 2014; Published 9 June 2014

Academic Editor: Philip H. Kass

Copyright © 2014 Jackie M. Wypij and David A. Heller. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. V. Bitetto, A. K. Patnaik, S. C. Schrader, and S. C. Mooney, “Osteosarcoma in cats: 22 cases (1974–1984),” Journal of the American Veterinary Medical Association, vol. 190, no. 1, pp. 91–93, 1987. View at Google Scholar · View at Scopus
  2. E. Heldmann, M. A. Anderson, and C. Wagner-Mann, “Feline Osteosarcoma: 145 cases (1990–1995),” Journal of the American Animal Hospital Association, vol. 36, no. 6, pp. 518–521, 2000. View at Google Scholar · View at Scopus
  3. P. J. Quigley, A. Leedale, and I. M. P. Dawson, “Carcinoma of mandible of cat and dog simulating osteosarcoma,” Journal of Comparative Pathology, vol. 82, no. 1, pp. 15–18, 1972. View at Google Scholar · View at Scopus
  4. P. J. Quigley and A. H. Leedale, “Tumors involving bone in the domestic cat: a review of fifty-eight cases,” Veterinary Pathology, vol. 20, no. 6, pp. 670–686, 1983. View at Google Scholar · View at Scopus
  5. R. E. Coleman, “Clinical features of metastatic bone disease and risk of skeletal morbidity,” Clinical Cancer Research, vol. 12, no. 20, pp. 6243s–6249s, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Mercadante, “Malignant bone pain: pathophysiology and treatment,” Pain, vol. 69, no. 1-2, pp. 1–18, 1997. View at Google Scholar
  7. A. H. Sparkes, R. Heiene, B. D. X. Lascelles et al., “ISFM and AAFP consensus guidelines. Long-term use of NSAIDs in cats,” Journal of Feline Medicine and Surgery, vol. 12, no. 7, pp. 521–538, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. FDA announces addition of boxed warning to METACAM (meloxicam) labels, FDA, Center for Veterinary Medicine, 2010, http://www.fda.gov/AnimalVeterinary/NewsEvents/CVMUpdates/ucm231254.htm.
  9. A. Lipton, “Implications of bone metastases and the benefits of bone-targeted therapy,” Seminars in Oncology, vol. 37, supplement 2, pp. S15–S29, 2010. View at Google Scholar · View at Scopus
  10. J. F. Guest, J. P. Clegg, A. M. Davie, and E. McCloskey, “Costs and consequences of using pamidronate compared with zoledronic acid in the management of breast cancer patients in the UK,” Current Medical Research and Opinion, vol. 21, no. 5, pp. 805–815, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Lipton, E. Small, F. Saad et al., “The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronate,” Cancer Investigation, vol. 20, no. 2, pp. 45–54, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. J. R. Berenson, “Antitumor effects of bisphosphonates: from the laboratory to the clinic,” Current Opinion in Supportive and Palliative Care, vol. 5, no. 3, pp. 233–240, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. T. M. Fan, L. P. de Lorimier, S. C. Charney et al., “Evaluation of intravenous pamidronate administration in 33 cancer-bearing dogs with primary or secondary bone involvement,” Journal of Veterinary Internal Medicine, vol. 19, no. 1, pp. 74–80, 2005. View at Publisher · View at Google Scholar
  14. T. M. Fan, L. P. de Lorimier, L. D. Garrett, and H. I. Lacoste, “The bone biologic effects of zoledronate in healthy dogs and dogs with malignant osteolysis,” Journal of Veterinary Internal Medicine, vol. 22, no. 2, pp. 380–387, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. T. M. Fan, L.-P. De Lorimier, K. O'Dell-Anderson, H. I. Lacoste, and S. C. Charney, “Single-agent pamidronate for palliative therapy of canine appendicular osteosarcoma bone pain,” Journal of Veterinary Internal Medicine, vol. 21, no. 3, pp. 431–439, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. T. M. Fan, S. C. Charney, L. P. de Lorimier et al., “Double-blind placebo-controlled trial of adjuvant pamidronate with palliative radiotherapy and intravenous doxorubicin for canine appendicular osteosarcoma bone pain,” Journal of Veterinary Internal Medicine, vol. 23, no. 1, pp. 152–160, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. M. L. Oblak, S. E. Boston, G. Higginson et al., “The impact of pamidronate and chemotherapy on survival times in dogs with appendicular primary bone tumors treated with palliative radiation therapy,” Veterinary Surgery, vol. 41, no. 3, pp. 430–435, 2012. View at Google Scholar
  18. J. L. Whitney, V. R. D. Barrs, M. R. Wilkinson, K. A. Briscoe, and J. A. Beatty, “Use of bisphosphonates to treat severe idiopathic hypercalcaemia in a young Ragdoll cat,” Journal of Feline Medicine and Surgery, vol. 13, no. 2, pp. 129–134, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. R. A. Hostutler, D. J. Chew, J. Q. Jaeger et al., “Uses and effectiveness of pamidronate disodium for treatment of dogs and cats with hypercalcemia,” Journal of Veterinary Internal Medicine, vol. 19, no. 1, pp. 29–33, 2005. View at Google Scholar
  20. D. Waldron, V. Pettigrew, M. Turk et al., “Progressive ossifying myositis in a cat,” Journal of the American Veterinary Medical Association, vol. 187, no. 1, pp. 64–65, 1985. View at Google Scholar · View at Scopus
  21. J. M. Wypij, T. M. Fan, R. L. Fredrickson, A. M. Barger, L. P. de Lorimier, and S. C. Charney, “In vivo and in vitro efficacy of zoledronate for treating oral squamous cell carcinoma in cats,” Journal of Veterinary Internal Medicine, vol. 22, no. 1, pp. 158–163, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. H. I. Lacoste, Managing pathological bone resorption in canine osteosarcoma [M.S. thesis], University of Illinois at Urbana-Champaign, 2007.
  23. J. A. Ashton, J. P. Farese, R. J. Milner, L. M. Lee-Ambrose, and J. M. van Gilder, “Investigation of the effect of pamidronate disodium on the in vitro viability of osteosarcoma cells from dogs,” American Journal of Veterinary Research, vol. 66, no. 5, pp. 885–891, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Leyvraz, U. Hess, G. Flesch et al., “Pharmacokinetics of pamidronate in patients with bone metastases,” Journal of the National Cancer Institute, vol. 84, no. 10, pp. 788–792, 1992. View at Google Scholar · View at Scopus
  25. Novartis, Aredia (pamidronate disodium), drug package insert, 2012.
  26. “Veterinary cooperative oncology group (VCOG)Veterinary cooperative oncology group—common terminology criteria for adverse events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1. 1.,” Veterinary and Comparative Oncology, 2011. View at Publisher · View at Google Scholar
  27. Sagent Pharmaceuticals I. Pamidronate disodium—MSDS, 2009.
  28. CIBA-GEIGY Corporation, Pamidronate disodium for injection—MSDS, 1991.
  29. P. A. Meyers, J. H. Healey, A. J. Chou et al., “Addition of pamidronate to chemotherapy for the treatment of osteosarcoma,” Cancer, vol. 117, no. 8, pp. 1736–1744, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. A. Kyrgidis, T. Tzellos, K. Toulis et al., “An evidence-based review of risk-reductive strategies for osteonecrosis of the jaws among cancer patients,” Current Clinical Pharmacology, vol. 8, no. 2, pp. 124–134, 2013. View at Google Scholar
  31. A. Watters, H. Hansen, T. Williams et al., “Intravenous bisphosphonate-related osteonecrosis of the jaw: long-term follow-up of 109 patients,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, vol. 115, no. 2, pp. 192–200, 2012. View at Google Scholar
  32. D. Powell, C. Bowler, T. Roberts et al., “Incidence of serious side effects with intravenous bisphosphonate: a clinical audit,” QJM, vol. 105, no. 10, pp. 965–971, 2012. View at Google Scholar
  33. M. A. Perazella and G. S. Markowitz, “Bisphosphonate nephrotoxicity,” Kidney International, vol. 74, no. 11, pp. 1385–1393, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. Boeringer Ingelheim Vetmedica I. Metacam (meloxicam, 5 mg/mL) solution for injection, package insert for cats, 2010.
  35. R. Chun, “Common malignant musculoskeletal neoplasms of dogs and cats,” Veterinary Clinics of North America: Small Animal Practice, vol. 35, no. 5, pp. 1155–1167, 2005. View at Publisher · View at Google Scholar · View at Scopus
  36. S. K. Liu, H. D. Dorfman, and A. K. Patnaik, “Primary and secondary bone tumours in the cat,” Journal of Small Animal Practice, vol. 15, no. 3, pp. 141–156, 1974. View at Google Scholar · View at Scopus
  37. B. K. Wobeser, B. A. Kidney, B. E. Powers et al., “Diagnoses and clinical outcomes associated with surgically amputated feline digits submitted to multiple veterinary diagnostic laboratories,” Veterinary Pathology, vol. 44, no. 3, pp. 362–365, 2007. View at Publisher · View at Google Scholar · View at Scopus
  38. S. Mukaratirwa, J. S. van der Linde-Sipman, and E. Gruys, “Feline nasal and paranasal sinus tumours: clinicopathological study, histomorphological description and diagnostic immunohistochemistry of 123 cases,” Journal of Feline Medicine and Surgery, vol. 3, no. 4, pp. 235–245, 2001. View at Publisher · View at Google Scholar · View at Scopus
  39. B. C. Gilger, S. A. McLaughlin, R. D. Whitley, and J. C. Wright, “Orbital neoplasms in cats: 21 cases (1974–1990),” Journal of the American Veterinary Medical Association, vol. 201, no. 7, pp. 1083–1086, 1992. View at Google Scholar · View at Scopus
  40. M. G. O'Brien, S. J. Withrow, R. C. Straw et al., “Total and partial orbitectomy for the treatment of periorbital tumors in 24 dogs and 6 cats: a retrospective study,” Veterinary Surgery, vol. 25, no. 6, pp. 471–479, 1996. View at Publisher · View at Google Scholar
  41. J. H. Rossmeisl Jr, O. I. Lanz, D. R. Waldron et al., “Surgical cytoreduction for the treatment of non-lymphoid vertebral and spinal cord neoplasms in cats: Retrospective evaluation of 26 cases (1990–2005),” Veterinary and Comparative Oncology, vol. 4, no. 1, pp. 41–50, 2006. View at Google Scholar
  42. N. J. Bacon, R. L. Gilbert, D. E. Bostock, and R. A. S. White, “Total ear canal ablation in the cat: indications, morbidity and long-term survival,” Journal of Small Animal Practice, vol. 44, no. 10, pp. 430–434, 2003. View at Google Scholar · View at Scopus
  43. C. A. London, R. R. Dubilzeig, D. M. Vail et al., “Evaluation of dogs and cats with tumors of the ear canal: 145 cases (1978–1992),” Journal of the American Veterinary Medical Association, vol. 208, no. 9, pp. 1413–1418, 1996. View at Google Scholar
  44. M. S. Levy, G. Mauldin, A. S. Kapatkin et al., “Nonlymphoid vertebral canal tumors in cats: 11 cases (1987–1995),” Journal of the American Veterinary Medical Association, vol. 210, no. 5, pp. 663–664, 1997. View at Google Scholar
  45. R. Sternberg, J. Wypij, and A. M. Barger, “An overview of multiple myeloma in dogs and cats,” Veterinary Medicine, vol. 104, no. 10, pp. 468–476, 2009. View at Google Scholar · View at Scopus