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Veterinary Medicine International
Volume 2014, Article ID 698741, 9 pages
Research Article

Effect of Three Colostrum Diets on Passive Transfer of Immunity and Preweaning Health in Calves on a California Dairy following Colostrum Management Training

1Veterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, 18830 Road 112, Tulare, CA 93274, USA
2Department of Veterinary Medicine & Surgery, Veterinary Medicine Teaching Hospital, College of Veterinary Medicine, University of Missouri, 900 E. Campus Drive, Columbia, MO 65211, USA
3Departamento de Producción y Sanidad Animal, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Moncada, 46113 Valencia, Spain
4Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4
5The Saskatoon Colostrum Co. Ltd., 30 Molaro Pl, Saskatoon, SK, Canada S7K 6A2
6Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA

Received 14 October 2013; Revised 20 January 2014; Accepted 18 March 2014; Published 16 April 2014

Academic Editor: Alexander Rodriguez-Palacios

Copyright © 2014 Deniece R. Williams et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Following colostrum management training, a randomized field trial was conducted on a California dairy to determine the effect of supplementing pooled colostrum with either colostrum-derived replacer (CDR) or second-milking colostrum (transition milk) on failure of passive transfer (FPT) and preweaning morbidity risks. A total of 166 calves were randomly assigned to 4L first-milking pooled colostrum (treatment 1), 2L first-milking pooled colostrum and 2L of CDR (treatment 2), or 2L first-milking pooled colostrum and 2L second-milking pooled colostrum (treatment 3). Mean 24-hour serum TP and IgG for treatments 2 (TP 5.2 g/dL, IgG 15.9 g/L) and 3 (TP 5.4 g/dL, IgG 18.3 g/L) did not statistically differ but were significantly lower than for treatment 1 (TP 5.9 g/dL, IgG 24.6 g/L). Risk of FPT did not differ for treatments 1, 2, and 3 (0.0%, 9.3%, and 1.9%, resp.). Similarly, the preweaning risk of diarrhea (81.0%, 92.5%, and 87.0%, resp.) or pneumonia (6.9%, 13.2%, and 18.5%, resp.) did not differ between treatments. Feeding 4L first-milking pooled colostrum resulted in adequate passive transfer. When first-milking pooled colostrum quantity is inadequate, CDR or second-milking pooled colostrum can be used to supplement the required colostrum volume and IgG mass without adversely affecting the risks of FPT or preweaning diarrhea and pneumonia.