Platelet-Rich Gel Supernatants Stimulate the Release of Anti-Inflammatory Proteins on Culture Media of Normal Equine Synovial Membrane Explants

Table 1

Mean (mean standard error) of the concentration of the molecules evaluated in both leukocyte and platelet-rich gel (L-PRG) and pure platelet-rich gel (P-PRG) supernatants and synovial fluid.

Variable	Fluid
	L-PRG	P-PRG	Synovial fluid
TGF- (pg/mL)	1669.2 ± 313.2	1369.2 ± 21.4	1413.8 ± 4.8
PDGF-BB (pg/mL)	3069. 9 ± 1261.6	383.8 ± 80.9^a	60.5 ± 0.9^a
TNF- (pg/mL)	60 ± 0.5^a,b	59 ± 1.4^a	66.7 ± 3.3^b
IL-4 (pg/mL)	75.7 ± 9.3^a	61.1 ± 1.52^a	101.8 ± 33.7^b
IL-1ra (pg/mL)	160.4 ± 68.0	58.7 ± 3.1^a	77.8 ± 10.7
HA (ng/mL)	6.9 ± 2.9	2.3 ± 1.08	53017.6 ± 12140^a

^a-bLowercase letters denote significant differences ( < 0.01) between groups in the same column by Tukey test.