Effect of Moxidectin Treatment at Peripartum on Gastrointestinal Parasite Infections in Ewes Raised under Tropical Andes High Altitude Conditions

Table 1

FECR induced by moxidectin strategic treatment of periparturient ewes during the same reproductive cycle.

Time of treatment	Evaluated period	Mean FEC ± SEM		Efficacy of treatment
		Untreated; control ewes	Treated ewes; and	% FECR	95% CI
Before lambing ()	Before treatment	1705 ± 537	1060 ± 314	—	—
	15 days after treatment (PEMox)	745 ± 351	3 ± 3	99.3	97–100
	Late postpartum (PPERPre)	4168 ± 1417	217 ± 172	94.8	66.2–99.6
	Preweaning (PWPer)	2582 ± 1205	123 ± 59	95.2	79.4–98.9
48 h after lambing ()	Before treatment	1277 ± 491	1043 ± 358	—	—
	15 days after treatment (PEMox)	1205 ± 316	27 ± 18	96.1	89.1–100
	Late postpartum (PPRPre)	4168 ± 1417	136 ± 64	96.7	85.9–99.5
	Preweaning (PWPer)	2582 ± 1205	193 ± 140	92.5	53–98.8

: late pregnancy treated group; : 48 hours postlambing treated group; PE_Mox: posttreatment efficacy induced by moxidectin; PPER_Pre: PPER prevention induced by moxidectin; PW_Per: preweaning moxidectin persistency; FEC: fecal egg count; SEM: standard error of mean; FECR: fecal egg count reduction; 95% CI: 95% confidence intervals. Three C ewes with high FEC and associated clinical signs were excluded after intermediate postpartum period due to Mox treatment by ethical considerations and their data were not included in the analysis. Significant effect of treatments (one-way ANOVA and Tukey tests, ) in FEC by evaluated period.