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Veterinary Medicine International
Volume 2016, Article ID 1048257, 5 pages
Research Article

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

1Veterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Via G. Celoria 10, 20133 Milan, Italy
2Centro de Transfusión Veterinario (CTV), Arturo Soria 267, 28033 Madrid, Spain
3Clinical Veterinary Hospital, CEU Cardenal Herrera University, Alfara del Patriarca, 46115 Valencia, Spain
4Laboratorio de Análisis Clínico, Hospital Clínico Veterinario, Universidad Alfonso X el Sabio, Avenida de la Universidad, Villanueva de la Cañada, 28691 Madrid, Spain

Received 11 October 2015; Accepted 10 February 2016

Academic Editor: Remo Lobetti

Copyright © 2016 Eva Spada et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aims of this study were to evaluate the prevalence of Dog Erythrocyte Antigens (DEA) 1, 4, and 7 in Ibizan hounds, to compare the results with the prevalence of DEA in Spanish greyhounds, and to determine the risk of sensitization following the first transfusion of blood not typed for DEA 1 and the probability of an acute hemolytic reaction following a second incompatible transfusion using untyped DEA 1 blood. DEA 1, 4, and 7 status was determined in 92 Ibizan hounds. Results were compared with the previously reported prevalence in Spanish greyhounds. The risks of sensitization and of a hemolytic transfusion reaction were determined amongst Ibizan hounds and between Ibizan hounds and Spanish greyhounds. The prevalence of DEA 1, 4, and 7 was 75%, 98.9%, and 25%, respectively. There was a significantly higher expression of DEA 1 and 7 in Ibizan hounds than in Spanish greyhounds. The probability of sensitization of a recipient dog to DEA 1 with transfusions amongst Ibizan hounds was 18.5% and between Ibizan hounds and Spanish greyhounds was 13.7%. The probability of an acute hemolytic reaction in each group was 3.5% and 1.9%, respectively. There is a higher prevalence of DEA 1 and 7 in Ibizan hounds than in other sighthounds.