Respiratory Support for Pharmacologically Induced Hypoxia in Neonatal Calves

Figure 3

Arterial partial pressure of carbon dioxide () following respiratory support by oxygen insufflation or continuous positive airway pressure (CPAP). Values are shown as median (horizontal line) and quartiles and range immediately after catheter placement (T0, baseline), 10 minutes following sedation (T1, sedation), following 10 minutes of oxygen supplementation (O₂), following 10 minutes of CPAP, and after 10 minutes of breathing ambient air following respiratory support (T3, rest, and T5, recovery). Individual results following respiratory support (CPAP or O₂ insufflation) are shown at T2 and T4. Order of respiratory support at T2 (CPAP or O₂ insufflation) was randomly assigned to replicate groups of paired calves. The alternate treatment (O₂ insufflation or CPAP) was administered at T4. CPAP was associated with significantly lower values than was evident following O₂ insufflation at T2 ().