Status Epilepticus due to Intraperitoneal Injection of Vehicle Containing Propylene Glycol in Sprague Dawley Rats

Table 1

Summary of animals described within the case report.

Animal; number	Evaluation	50% dextrose administration	Outcome
1	Postmortem necropsy	No	Normal, no gross abnormalities
2	Test hypothesis that seizures were due to hypoglycemia	Oral/rectal	Administration of 50% dextrose and diagnosis of hypoglycemia
3	Blood glucose test	Oral/rectal	Animals were not hypoglycemic; seizures were due to compound injected
4	Identifying component of drug, tested diluent only	Oral/rectal	Animals had seizures
5	Identifying component of drug, tested propylene glycol only	Oral/rectal	Animals had seizures
6	Identifying component of drug, tested corn oil only	No	Animals did not have seizures
7	Cardiac puncture for blood test	No	Diagnosis of hemolysis and lactic acidosis which may have led to seizures