Assessment of Pasteurella multocida A Lipopolysaccharide, as an Adhesin in an In Vitro Model of Rabbit Respiratory Epithelium

Table 2

Grading the severity of the lesions using H&E, adapted from Bernet et al. [29].

(a)

Grade	Severity	Description
−	Absent	(i) Cells with normal activity; (ii) Normal architecture is readily visible
+	Light	(i) Cells with scant activity; (ii) Lesions are observed with some difficulty
++	Moderate	(i) Cells with moderate activity; (ii) Lesions are easily observed, with normal architecture still visible
+++	Severe	(i) Cells are very active; (ii) Lesions are easily observed; the normal architecture is not identified

(b)

Extension	Description
Focal	F: lesion in an area comprising less than 10% of the section
Multifocal	M: lesions in more than two areas, each comprising less than 10% of the section
Diffuse	G: multiple areas or an area greater than 50% of the section