Assessment of Pasteurella multocida A Lipopolysaccharide, as an Adhesin in an In Vitro Model of Rabbit Respiratory Epithelium

Table 3

Grading of the lesions after each treatment (H&E): desquamated cells (DQ); increased goblet cells activity (AGC); cilia loss (CL); presence of intracytoplasmic vacuoles (IV); and dead cells (DC).

Treatment	DQ	AGC	CL	IV	DC
(1) Negative control	−	−	−	−	−
(2) Exposure to P. multocida	++	++	+	+	+
(3) Simultaneous exposure to P. multocida LPS and P. multocida	+++	+++	++	++	++
(4) Exposure to P. multocida LPS followed by P. multocida 30 min later	+++	+++	++	++	++
(5) Exposure to P. multocida followed by P. multocida LPS 30 min later	++	++	++	++	++
(6) Exposure to LPS of P. multocida	+++	+++	+	+	+