Serum Symmetric Dimethylarginine as an Early Marker of Excretory Dysfunction in Canine Leishmaniosis (L. infantum) Induced Nephropathy

Table 2

Odds ratio for being classified in Group A or Group B after six months of follow-up depending on several cut-off values of kidney parameters on the day of diagnosis in 39 dogs with leishmaniosis.

Values on the day of diagnosis	Odds ratio for being classified in Group A	Odds ratio for being classified in Group B
SDMA > 19 µg/dL	0.21 (0.04–1.16)	4.76 (0.85–26.47)	0.074
SDMA ≥ 25 µg/dL	0.03 (0.001–0.605)	34.2 (1.65–708.19)	0.022
UPC > 0.5	0.047 (0.005–0.429)	21.11 (2.33–191.17)	0.0067
UPC > 5	0.03 (0.001–0.605)	34.2 (1.65–708.19)	0.022
Creatinine ≥ 1.4 mg/dL	0.021 (0.001–0.424)	48.23 (2.35–986.19)	0.00118

Expressed as odds ratio and its 95% confidence interval. value. Group A: dogs with no evidence of renal disease based on the IRIS staging for CKD [25] after six months of diagnosis of leishmaniosis. Group B: dogs with CKD classified as IRIS stage 1 to stage 3 and dogs euthanized or dead due to renal disease after six months of diagnosis of leishmaniosis. : significance level (Mann–Whitney test). UPC: urinary protein/creatinine ratio.