Veterinary Medicine International / 2018 / Article / Tab 2

Research Article

Serum Symmetric Dimethylarginine as an Early Marker of Excretory Dysfunction in Canine Leishmaniosis (L. infantum) Induced Nephropathy

Table 2

Odds ratio for being classified in Group A or Group B after six months of follow-up depending on several cut-off values of kidney parameters on the day of diagnosis in 39 dogs with leishmaniosis.

Values on the day of diagnosisOdds ratio for being classified in Group AOdds ratio for being classified in Group B

SDMA > 19 µg/dL0.21 (0.04–1.16)4.76 (0.85–26.47)0.074
SDMA ≥ 25 µg/dL0.03 (0.001–0.605)34.2 (1.65–708.19)0.022
UPC > 0.50.047 (0.005–0.429)21.11 (2.33–191.17)0.0067
UPC > 50.03 (0.001–0.605)34.2 (1.65–708.19)0.022
Creatinine ≥ 1.4 mg/dL0.021 (0.001–0.424)48.23 (2.35–986.19)0.00118

Expressed as odds ratio and its 95% confidence interval. value. Group A: dogs with no evidence of renal disease based on the IRIS staging for CKD [25] after six months of diagnosis of leishmaniosis. Group B: dogs with CKD classified as IRIS stage 1 to stage 3 and dogs euthanized or dead due to renal disease after six months of diagnosis of leishmaniosis. : significance level (Mann–Whitney test). UPC: urinary protein/creatinine ratio.

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