Review Article

Endoscopic Biopsies and Histopathological Findings in Diagnosing Chronic Gastrointestinal Disorders in Dogs and Cats

Table 1

Criteria for histopathological evaluation of the GI lining.

StructureClassification of lesions

I—epithelium
Size of enterocytesNo lesions (0) to significantly changed (3)
Continuity of structureNo damage (0) to significantly damage (3)
Number and size of goblet cells/100 enterocytesNormal (0) to significantly changed, large quantity of mucus (3)
Cellular infiltrationNone (0) to significant infiltration (3)
II— lamina propria
Cellular infiltrationNone (0) to significant infiltration (3)
FibrosisNone (0) to significant fibrosis (3)
LymphangiectasiaNone (0) to significant lymphangiectasia (3)
III—crypts
AtrophyNone (0) to significant atrophy (3)
Hypertrophyshape changeNone (0) to significant hypertrophy (3)
ProliferationhyperplasiaNone (0) to significant proliferation (3)
Diversification of goblet cellsNone (0) to significant diversification (3)
Presence of inflammatory cellsNone (0) to significant infiltration (3)
IV—villi
Structure (length, width, and shape)Normal (0) to significant change in structure (3)