In Vitro Antiviral Activity of Green Tea Polyphenon-60 against Avian Paramyxoviruses

Table 1

Inhibitory effect of polyphenon-60 on the growth of avian paramyxoviruses in CEF cells.

Strain	Virulence	The virus infectivity titers at 48 h p.i in the presence of polyphenon-60 (log2 HAU)
		100 (μg/ml)	50 (μg/ml)	20 (μg/ml)	0 (μg/ml)
NDV/Sato/30	V	2.3 ± 0.6	2.3 ± 1.2	2.7 ± 1.2	3.3 ± 0.6
NDV/Komarov/40	M	3.3 ± 0.6^a	2.7 ± 0.6^a	4.3 ± 0.6^b	4.7 ± 0.6^b
NDV/Hitcher B1/48	L	1.7 ± 1.2^a	1.7 ± 0.6^a	4.3 ± 0.6^b	5.3 ± 0.6^b
NDV/Miyadera/51	V	2.3 ± 1.5	2.3 ± 1.2	2.7 ± 0.6	3.0 ± 1.0
NDV/Ishii/62	L	1.3 ± 0.6^a	1.7 ± 0.6^a	4.3 ± 0.6^b	5.3 ± 0.6^b
NDV/Taka/73	V	2.0 ± 1.0	2.0 ± 0.0	2.7 ± 0.6	2.7 ± 0.6
NDV/Niigata/85	V	3.0 ± 1.0	3.0 ± 0.0	3.0 ± 1.0	3.0 ± 1.7
NDV/Tochigi/95	M	2.7 ± 0.6^ab	3.7 ± 0.6^b	4.3 ± 0.6^b	4.7 ± 0.6^b
NDV/Tokyo/96	V	2.7 ± 0.6	2.7 ± 1.0	2.7 ± 0.6	2.7 ± 1.0
NDV/Ibaraki-2/99	V	2.0 ± 0.0	2.0 ± 1.0	2.3 ± 0.6	2.0 ± 1.0
NDV/Kumamoto/2000	M	3.0 ± 1.0^b	2.3 ± 0.6^ab	4.0 ± 1.0^b	4.7 ± 0.6^b
NDV/Chiba/2001	V	2.7 ± 0.6	2.7 ± 1.2	2.7 ± 0.6	2.7 ± 1.5
APMV-2/Yucaipa/56	NA	2.3 ± 1.2	2.7 ± 0.6	2.7 ± 0.6	2.7 ± 0.6
APMV-2/Bangor/73	NA	2.0 ± 1.0	2.3 ± 0.6	2.7 ± 0.6	2.7 ± 1.5
APMV-3/Winsconsin/68	NA	3.7 ± 0.6^a	3.3 ± 0.6^a	5.3 ± 0.6^b	5.7 ± 0.6^b
APMV-7/Tennessee/75	NA	1.0 ± 0.0^ab	1.7 ± 1.2^b	2.0 ± 1.0^b	2.3 ± 0.6^b

L: lentogenic; M: mesogenic; V: velogenic; NA: not applicable. Data were expressed as the mean ± SD of three independent experiments. Means with different superscript letters in a row were significantly different ().