Histopathological Profiles of Rats (Rattus norvegicus) Induced with Streptozotocin and Treated with Aqueous Root Extracts of Ruellia tuberosa L.

Table 2

Serum and pancreas MDA levels on rats at the end of the treatment, in week 4, in groups 1 to 5.

Group	Serum MDA level (μg/dL)	Changes	Pancreas MDA level (μg/dL)	Changes
1 (normal)	1.27 ± 0.18a		0.237 ± 0.03a
2 (diabetic)	6.96 ± 0.41e	448.03%	0.75 ± 0.12 d	216.45%
3 (dose of 250 mg/kg)	6.04 ± 0.15 d	13.22%	0.69 ± 0.09 d	8.0%
4 (dose of 500 mg/kg)	4.55 ± 0.33c	34.63%	0.66 ± 0.07c	12.0%
5 (metformin 200 mg/kg)	2.35 ± 0.45 b	66.24	0.367 ± 0.03 b	51.07%

Different notations indicate significant differences between treatments (p < 0.05).