In Vivo Analysis of Extract of Leaves of Mistletoe as a Benalu Duku: Clinical Chemical Value Associated with Histopathology, Liver, Kidneys, and Lethal Dose Determinate

Table 1

The parameters of the clinical chemistry of rats after giving progesterone-like compounds single-dose administrations in trial groups compared to control groups after giving 0.5 mL of Aqua Pro injection.

Groups	Clinical chemistry assessment	No. of rats					Coefficient variation (%)
		1	2	3	4	5
Control group	AST (U/L)	170	195	90	95	100	37.586
	ALT (U/L)	80	110	70	50	60	31.111
	Creatinine (mg/dl)	0.81	0.88	0.65	0.64	0.72	14.054
	BUN (mg/dL)	18.50	18.90	19.23	19.26	19	1.618
Group I (50 mg/kg BW)	AST (U/L)	135	120	120	180	110	1.618
	ALT (U/L)	80	75	80	80	79	2.751
	Creatinine (mg/dL)	0.67	0.66	0.68	0.66	0.68	1.492
	BUN (mg/dL)	17.50	19	17.50	19.50	18.50	4.859
Group II (55 mg/kg BW)	AST (U/L)	100	125	120	100	125	11.352
	ALT (U/L)	75	75	80	70	70	5.653
	Creatinine (mg/dL)	1.41	0.78	0.88	0.85	0.95	25.770
	BUN (mg/dL)	24.60	28.90	27.30	28.50	27.40	9.310
Group III (60 mg/kg BW)	AST (U/L)	125	140	120	125	125	5.971
	ALT (U/L)	75	60	80	70	80	11.462
	Creatinine (mg/dL)	0.75	0.77	0.68	1.02	1.01	4.532
	BUN (mg/dL)	25.20	24.40	26.60	31.50	32.10	12.872
Group IV (65 mg/kg BW)	AST (U/L)	145	120	111	114	112	11.784
	ALT (U/L)	70	80	81	84	84	7.220
	Creatinine (mg/dL)	0.76	0.69	0.71	0.68	0.69	4.533
	BUN (mg/dL)	17.80	18.40	19.70	19.30	19.60	4.356
Group V (70 mg/kg BW)	AST (U/L)	110	170	80	95	110	30.270
	ALT (U/L)	50	55	60	65	70	13.177
	Creatinine (mg/dL)	0.77	0.89	0.85	0.71	0.79	8.728
	BUN (mg/dL)	25.70	26.70	25.40	26.50	26.50	12.190
Group VI (75 mg/kg BW)	AST (U/L)	120	115	115	110	123	4.336
	ALT (U/L)	70	81	75	75	83	6.790
	Creatinine (mg/dL)	0.69	0.67	0.76	0.82	0.94	14.05
	BUN (mg/dL)	27.60	28.80	28.70	29.50	29.80	2.954