Effect of Allicin and Artesunate Combination Treatment on Experimental Mice Infected with Plasmodium berghei

Table 2

Effect of allicin and its combination with ART on PCV in PbANKA infection in mice.

Group	Dose (mg/kg)			PCV (%)
	UN	Allicin	ART	D0	D4	% change
Single	10 ml/kg of 20% Tween-80	—	—	53.32 + 0.85	41.92 + 1.21	−21.38
	—	14	—	52.78 + 1.21	46.26 + 0.69	−12.35
	—	—	5	53.19 + 0.98	47.72 + 0.58	−10.28
Combination (1 : 1)	ED50	14	5	52.62 + 0.73	51.74 + 0.95	−1.67^,##
	ED50 1/2	7	2.5	53.54 + 0.87	51.83 + 1.03	−3.19^,##
	ED50 1/4	3.5	1.25	52.29 + 0.61	46.48 + 0.63	−11.11
	ED50 1/8	1.75	0.625	53.29 + 0.81	42.15 + 1.13	−20.90

and compared to UN. ^## compared to allicin and ART.