Effect of Allicin and Artesunate Combination Treatment on Experimental Mice Infected with Plasmodium berghei

Table 3

Effect of allicin and its combination with ART on BW in PbANKA infection in mice.

Group	Dose (mg/kg)			BW (g)
	UN	Allicin	ART	D0	D4	% change
Single	10 ml/kg of 20% Tween-80	—	—	26.51 + 1.13	20.05 + 0.72	−24.37
	—	14	—	27.12 + 0.52	25.58 + 0.26	−5.68
	—	—	5	26.34 + 1.23	25.19 + 0.82	−4.37
Combination (1:1)	ED50	14	5	26.47 + 0.86	26.53 + 0.34	0.23^,##
	ED50 1/2	7	2.5	26.71 + 0.91	26.65 + 0.63	−0.22^,##
	ED50 1/4	3.5	1.25	25.59 + 1.06	24.91 + 0.93	−2.66
	ED50 1/8	1.75	0.625	26.69 + 0.93	20.17 + 0.51	−24.43

and compared to UN. ^## compared to allicin and ART.