Development of an Optimal Model of Combined Radiation and Biological Lesions

Table 1

Dose-dependent survival rate of rabbits infected with Pasteurella cultures.

Group	Dose, m.c./animal	Dead animals rate/total number of animals	Mortality rate (%)
1	1 : 10·0010^−8	0/6	0
2	1 : 100·10^−7	1/6	16.66
3	1 : 1000·10^−6	2/6	33.33
4	1 : 10000·10^−5	3/6	50
5	1 : 100000·10^−4	5/6	83.3
6	1 : 1000000·10^−3	6/6	100
7	1 : 10000000·10^−2	6/6	100
8	1 : 100000000·10^−1	6/6	100
9	1 : 1000000000·10^9	6/6	100
10	Saline	0/6	0
11	Biological control	0/6	0

Calculation: (10 + 100)⋅(16.66 − 0) = 1832.6. (100 + 1000)·(33.33 − 16.66) = 18337. (1000 + 10000)·(50 − 33.33) = 183370. (10000 + 100000)·(83.3 − 50) = 3663000. (100000 + 1000000)·(100 − 83.3) = 18370000. (1000000 + 10000000)·(100 − 100) = 0. LD₅₀ = 22236539.6/200 = 111182.698 m.c./animal = 111182.898/3 = 37060.89 m.c./kg (3.7·10⁴ m.c./kg).