Prognostic Factors for Cancer-Specific Survival and Disease-Free Interval of Dogs with Mammary Carcinomas
Table 3
One-year corrected survival rates in 95 cases (4 failures) with available follow-up dataa.
Cancer-specific survival (n = 95)
Disease-free interval (n = 95)
n
Median survival (days)
Median 1-yearsurvival rate n (%)
n
Median survival (days)
Median 1-yearsurvival rate n (%)
Age
≤9.0 years
30
1.460
23 (76.67%)
30
1.460
23 (76.67%)
>9.0 years
65
365
31 (47.69%)
65
365
31 (47.69%)
0.001
0.001
Breed
Mixed-breed
27
730
15 (55.56%)
27
365
13 (48.15%)
Purebred
68
730
39 (57.35%)
68
730
35 (66.18%)
0.453
0.234
Type of food
Homemade food
2
380
0
2
197
0
Commercial diets
43
730
24 (55.81%)
43
730
23 (53.49%)
Commercial diets + meat
2
2.007
1 (50%)
2
2.007
1 (50%)
Commercial diets + homemade food
35
365
17 (48.57%)
35
365
14 (40%)
Commercial diets + snack
13
1.095
10 (76.92%)
13
1.095
9 (69.23%)
0.117
0.082
Ovariohysterectomy (OHE)
No
78
730
47 (60.26%)
78
730
42 (53.85%)
Yes
17
365
7 (41.17%)
17
365
6 (35.29%)
0.090
0.078
Pseudocyesis
Absent
88
730
50 (56.82%)
88
365
43 (48.86%)
Present
7
1.825
4 (57.14%)
7
1.825
4 (57.14%)
0.182
0.034
Hormone administration
No
81
730
45 (55.56%)
81
730
40 (49.38%)
Yes
14
730
9 (64.29%)
14
730
8 (57.14%)
0.714
0.636
History of previous disease
Negative
71
730
42 (59.15%)
71
730
37 (52.11%)
Positive
24
547
12 (50%)
24
365
11 (45.83%)
0.021
0.230
Clinical stage (TNM)
Initial (I–III)
74
730
45 (60.81%)
74
730
40 (54.05%)
Advanced (IV-V)
21
365
9 (42.86%)
21
365
8 (38.1%)
0.006
0.013
Surgical technique
Radical mastectomy
48
730
27 (56.25%)
48
730
25 (52.08%)
Other techniques
47
730
27 (57.45%)
47
365
23 (48.94%)
0.782
0.937
Tumor size
T1 (<2 cm)
49
730
27 (55.1%)
49
730
24 (48.98%)
T2 (2-3 cm)
20
547
10 (50%)
20
365
9 (45%)
T3 (>3 cm)
26
730
17 (65.38%)
26
730
15 (57.69%)
0.668
0.698
Histological type (n = 72)
Carcinoma in a mixed tumor
42
1.033
31 (73.81%)
42
1.095
27 (64.29%)
Solid carcinoma
15
365
6 (40%)
15
365
6 (40%)
Tubular carcinoma
11
730
6 (54.55%)
11
365
5 (45.45%)
0.298
0.264
Histological grade (n = 90)
Grade I
32
1.095
22 (68.75%)
32
1.095
21 (65.63%)
Grade II
27
1.095
19 (70.37%)
27
1.095
16 (59.62%)
Grade III
31
365
11 (35.48%)
31
180
9 (29.03%)
0.001
0.002
Distant metastasis
No
84
730
48 (58.54%)
84
730
42 (50%)
Yes
11
730
6 (54.55%)
11
730
6 (54.55%)
0.133
0.195
Ulceration
Absent
67
730
43 (64.18%)
67
730
40 (59.7%)
Present
28
365
11 (39.29%)
28
365
8 (28.57%)
0.003
0.001
aSurvival values are percentages for cumulative survival determined by the log-rank test. Significance level adopted was .P values in bold indicate significance.
