The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders

Figure 3

Schematic representation of intraarticular action of mesenchymal stem cells’ secretome. After intraarticular administration or delivery from the bloodstream, a lot of substances inherent to the extracellular vesicles are secreted and they act in the articular cartilage and environment, resulting in anti-inflammatory and anticatabolic effects, in addition to the stimulation of joint regeneration and resurfacing [67–75]. Figure created with Procreate® software (version 5.3.5, Savage Interactive Pty Ltd.).