Table 2: Results from question on common issues.

Choices (ordered by N)N

Overall loss in performance compared to native apps63
Suboptimal User Experience (UX)58
Immature frameworks (too cutting edge, too much risk, etc.)55
Suboptimal options for creating good User Interfaces (UI)50
Immature communities (too new/low activity, etc.)35
Hard to integrate with device API32
Hard to test/debug31
Security issues13
“Dealing with platform/OS/manufacturer quirks (especially Android)”1
“Least common denominator feature set: your app’s features are limited to the intersection of iPhone and Android’s features”1