Comprehensive Medical System for Early Diagnosis of Rheumatoid Arthritis Based on Autoimmune Antibodies

Table 6

Comparison of single and combined testing schemes for 4 indicators.

Test items	Sensitivity	Specificity	PPV	NPV	Accuracy	YI	Kappa
RF	73.4	89.8	88.6	71.2	75.03	0.53	0.47
Anti-CCP antibody	83.3	92.5	93.2	82.8	88	0.77	0.76
14-3-3	79	74.1	78.5	75	76.9	0.53	0.55
AKA	40.7	94.2	88.5	58.3	65	0.37	0.31
14-3-3+anti-CCP antibody	63.65	95.64	93.18	70.14	78.56	0.61	0.58
14-3-3/anti-CCP antibody	97.3	72.61	82.16	95.77	86	0.73	0.74
RF + AKA	43.85	94.35	88.42	59.07	66.22	0.38	0.35
RF/AKA	76.91	93	91.86	77.32	86.12	0.69	0.65
RF + anti-CCP antibody	62.59	99	98.16	70.07	79.36	0.65	0.601
RF/anti-CCP antibody	91.78	90.39	93.23	87.92	90.08	0.82	0.793