Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage

Table 2

Human/zebrafish Vwf domain conservation.

Domain	Identities	Positives	Human	zebrafish
	(%)	(%)	length	length
D1	51	70	352	351
D2	64	79	360	359
D′	51	71	90	88
D3	56	69	376	370
A1	36	57	220	233
A2	28	56	193	193
A3	42	58	202	207
D4	39	54	372	382
B1	58	73	35	34
B2	52	64	26	30
B3	67	83	25	25
C1	50	58	116	107
C2	48	63	119	117
CK	42	64	90	91
Total	46	62	2813	2812

Alignment of human and zebrafish amino acid sequences using BLAST (http://blast.ncbi.nlm.nih.gov/). Percentage identity represents exact amino acid matches, while positives indicate conserved substitutions. Domain length is in amino acids.