Assessment of Size-Dependent Antimicrobial and Cytotoxic Properties of Silver Nanoparticles
Figure 3
Cytotoxicity test of AgNPs to PBMCs and antimicrobial effect to Methylobacterium spp. (a) The numbers of live (blue) and dead (red) cells were counted for each sample. (b) 10 nm AgNPs displayed increased cytotoxicity in 0.5 mg/mL concentration between two different size particles. 1.0 mg/mL of 10 nm AgNPs showed the highest cytotoxicity to PBMCs comparable to the one from the positive control (DMSO). (c) Antimicrobial test of AgNPs against Methylobacterium spp. Both 100 and 10 nm AgNPs displayed strong antimicrobial effects in 0.5 mg/mL or higher concentration coincubated with the bacteria. 1.0 mg/mL of 10 nm AgNPs showed the equal killing efficiency as to the positive control (methanol). , , one-tailed Mann-Whitney U test.
