Research Article
A 3D Osteoblast In Vitro Model for the Evaluation of Biomedical Materials
Table 1
Parameters and scores for the qualitative assessment of the spheroids.
| ā | Score | ā | 1 | 2 | 3 | 4 |
| Regularity of shape | Mostly amorphous | Mostly irregular | Mostly regular spheroids | Completely spheroidal | Size | Too small | Small | Medium | Big | Repeatability | Strong variation in shape, size, and number | Variation in one or two parameters | Most parameters are similar | Very similar in all parameters | Handling | Very difficult | Difficult | Easy | Very easy | Stability | Always disintegrate | Disintegrate on a considerable proportion (after 2-3 days) | Most remain stable | All remain stable after 2-3 days |
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