A 3D Osteoblast In Vitro Model for the Evaluation of Biomedical Materials

Table 3

Time of formation and stability of spheroids produced with primary human or murine line cells, at an initial density of 20,000 cells ().

Cell type	Average time of aggregate formation	Limit of stability on culture
Primary human bone cells	7.1 ± 2.2 days	35 ± 5.5 days
MC3T3-E1	2.0 ± 0.6 days	20.6 ± 5.4 days