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Advances in Materials Science and Engineering
Volume 2015, Article ID 318696, 10 pages
http://dx.doi.org/10.1155/2015/318696
Research Article

Influence of Heat Treatment on Biocorrosion and Hemocompatibility of Biodegradable Mg-35Zn-3Ca Alloy

1Department of Dental Biomaterials and Institute of Biodegradable Material, Institute of Oral Bioscience and BK21 Plus Project, School of Dentistry, Chonbuk National University, Jeonju 561-756, Republic of Korea
2Division of Advanced Materials Engineering and Institute of Biodegradable Material, Chonbuk National University, Jeonju 561-756, Republic of Korea
3Department of New Drug Discovery and Development, Chungnam National University, Yuseong, Daejeon 305-764, Republic of Korea

Received 19 December 2014; Accepted 21 January 2015

Academic Editor: Jinghuai Zhang

Copyright © 2015 Jeong-Hui Ji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mg-35Zn-3Ca (wt.%) alloy containing nontoxic and biocompatible Zn and Ca as alloying elements was prepared and subjected to heat treatment and artificial aging for different duration of time to reduce its rate of degradation. Solution heat treatment was performed at 310°C while artificial aging was performed at 170°C for 0, 2.5, 5.0, 7.5, and 10.0 h and they were designated as AT0, AT1, AT2, AT3, and AT4, respectively. The finest and most homogenous reticulum was observed on the surface of the AT2 group. The result of immersion test in Hank’s balanced salt solution (HBSS) showed that the corrosion rate of the AT2 group was 2.32 mg/(cm2 day), which was significantly lower as compared to other groups . The hemolysis value was ≤5% in all groups, indicating no toxicity during short-term blood reaction.