Research Article
Ultrafine Resveratrol Particles: Supercritical Antisolvent Preparation and Evaluation In Vitro and In Vivo
Table 2
Orthogonal array design OA16 (4)5 and experimental results.
| | Trial number | | | | | MPS (μm) ± SD (n = 3) |
| | 1 | 1 | 1 | 1 | 1 | 1.79 ± 0.12 | | 2 | 1 | 2 | 2 | 2 | 1.89 ± 0.18 | | 3 | 1 | 3 | 3 | 3 | 0.82 ± 0.04 | | 4 | 1 | 4 | 4 | 4 | 1.31 ± 0.09 | | 5 | 2 | 1 | 2 | 3 | 2.18 ± 0.24 | | 6 | 2 | 2 | 1 | 4 | 1.49 ± 0.16 | | 7 | 2 | 3 | 4 | 1 | 1.03 ± 0.08 | | 8 | 2 | 4 | 3 | 2 | 1.09 ± 0.05 | | 9 | 3 | 1 | 3 | 4 | 0.76 ± 0.04 | | 10 | 3 | 2 | 4 | 3 | 1.44 ± 0.12 | | 11 | 3 | 3 | 1 | 2 | 0.82 ± 0.08 | | 12 | 3 | 4 | 2 | 1 | 0.7 ± 0.02 | | 13 | 4 | 1 | 4 | 2 | 0.93 ± 0.04 | | 14 | 4 | 2 | 3 | 1 | 0.93 ± 0.10 | | 15 | 4 | 3 | 2 | 4 | 1.61 ± 0.12 | | 16 | 4 | 4 | 1 | 3 | 1.27 ± 0.12 |
| | 1.45 ± 0.13 | 1.42 ± 0.12 | 1.34 ± 0.08 | 1.11 ± 0.06 | | | 1.45 ± 0.14 | 1.44 ± 0.10 | 1.60 ± 0.09 | 1.18 ± 0.12 | | | 0.93 ± 0.07 | 1.07 ± 0.06 | 0.90 ± 0.08 | 1.43 ± 0.14 | | | 1.19 ± 0.10 | 1.09 ± 0.12 | 1.18 ± 0.13 | 1.29 ± 0.08 | | | 0.52 | 0.37 | 0.70 | 0.32 | | | Optimal level | | | | | |
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= (mean particle size at )/4, the mean values of mean particle size for a certain factor at each level with standard deviation.
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