Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl₄-Induced Hepatotoxicity in Mice

Table 1

The four marketed polyherbal formulations (liquid) used in current study of activities against liver injury (compiled from the manufacturer’s instructions).

Formulations	Principal ingredients	Purpose	Standard dose
Heptaliv (S. B. Laboratories, Rjshahi, Bangladesh)	Each 5 ml extract contains Aphanamixis polystachya -1.52 gm, Woodfordia floribunda-0.24 gm, Piper longum-15.24 mg, Zingiber officinale-15.24 mg, Trifala-45.73 mg, and other ingredients	Jaundice, hepatic malfunction, liver inflammation, alcoholic liver disorder, liver cirrhosis, indigestion, constipation, and loss of appetite remedy	2–4 teaspoons 2 to 3 times daily.
Holyliv (GK pharma, station road, Tongi, Gazipur)	Each 5 ml extract contains Cichorium intybus root (400 mg), Cichorium intybus seed (200 mg), Rose damascene (200 mg), Nymphaea alba (100 mg), Borago officinalis (100 mg), Cuscuta, reflexa seed (150 mg), Rheum emodi (300 mg), and other ingredients.	Hepatitis, obstructive jaundice, edema, inflammation of uterus, pleurisy, constipation	2–3 teaspoons twice daily
Icturn (hamdard laboratories Bangladesh, Sonargaon, Narayangonj)	Each 5 ml extract contains Cichorium endivia root-400 gm, Cichorium endivia seed-200 mg, Rose damascene-200 mg, Nympaea nouchali-100 mg, Borago officinalis-100 mg, Cuscuta, reflexa seed-150 mg Rheum emodi-125 mg, and other ingredients.	Hepatitis, obstructive jaundice ascites constipation, alveolitis, pleurisy uterine inflammation, and metritis	2–3 teaspoons twice daily
J-deenar (janashastha pharmaceuticals, Dhaka, Bangladesh	Each 5 ml extract contains cuscuta leaf-400 mg, endive seeds-200 mg, male fern-200 mg, water lily-100 mg, borago gawjban-100 mg, cuscuta roots-150 mg, rhaw chine-125 mg and other ingredients	Hepatitis, jaundice, and constipation.	2 teaspoons 3 times daily after meal