Advances in Pharmacological and Pharmaceutical Sciences

Research Article

Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl4-Induced Hepatotoxicity in Mice

Table 4

Effect of Polyherbal formulations on the gain of body weight.
CCl4-induced hepatotoxicity methodCCl4+ phenobarbitone-induced method
GroupsChange in body weight (g)GroupsChange in body weight (g)
Group-11.50 ± 0.08Group-111.80 ± 0.07
Group-20.80 ± 0.03Group-120.93 ± 0.06
Group-31.20 ± 0.05Group-131.27 ± 0.07
Group-41.29 ± 0.06Group-141.39 ± 0.05
Group-51.23 ± 0.07Group-151.30 ± 0.08
Group-61.28 ± 0.04Group-161.39 ± 0.09
Group-71.37 ± 0.05Group-171.37 ± 0.07
Group-81.45 ± 0.07Group-181.44 ± 0.08
Group-91.25 ± 0.08Group-191.45 ± 0.08
Group-101.35 ± 0.06Group-201.57 ± 0.07
Each value is Mean ± S.E.M (n = 3). Group 4 = CCl4+ 5.2 ml/kg/day Holyliv, Group 5 = CCl4+ 2.6 ml/kg/day Heptaliv, Group 6 = CCl4+ 5.2 ml/kg/day Heptaliv, Group 7 = CCl4+ 2.6 ml/kg/day Icturn, Group 8 = CCl4+ 5.2 ml/kg/day Icturn, Group 9 = CCl4+ 2.6 ml/kg/day J-Deenar, Group 10 = CCl4+ 5.2 ml/kg/day J-Deenar. Group 11 = normal control, Group 12 = CCl4+ phenobarbitone control, Group 13 = CCl4+ phenobarbitone + 2.6 ml/kg/day Holyliv, Group 14 = CCl4+ phenobarbitone + 5.2 ml/kg/day Holyliv, Group 15 = CCl4 + phenobarbitone +2.6 ml/kg/day Heptaliv, Group 16 = CCl4+ phenobarbitone + 5.2 ml/kg/day Heptaliv, Group 17 = CCl4+ phenobarbitone + 2.6 ml/kg/day Icturn, Group 18 = CCl4+ phenobarbitone + 5.2 ml/kg/day Icturn, Group 19 = CCl4+ phenobarbitone + 2.6 ml/kg/day J-Deenar, Group 20 = CCl4+ phenobarbitone + 5.2 ml/kg/day J-Deenar.