the genedens chromosom archaea bacteria were long thought devoid pseudogen massiv increas avail genom sequenc whole genom comparison between close relat speci have identifi mutat have render numer gene inact compar analys sequenc archaeal genom reveal numer pseudogen which can constitut 86 annot code sequenc some genom the largest proport pseudogen creat gene truncat follow frameshift mutat within archaeal genom larg number pseudogen contain more than one inactiv mutat suggest pseudogen delet from genom more slowli archaea than bacteria although archaea seem retain pseudogen longer than bacteria most archaeal genom have uniqu repertoir pseudogen

M. W. J. van Passel

C. S. Smillie

H. Ochman

Gene decay in archaea

hyperthermus butylicus hyperthermophil neutrophil anaerob member archaeal kingdom crenarchaeota its genom consist singl circular chromosom 1667163 537 content total 1672 gene were annot which 1602 proteincod third specif butylicus contrast some other crenarcha genom high level gug uug start codon predict two cdc6 gene present neither could link unambigu origin replic mani predict metabol gene product associ ferment peptid mixtur includ sever peptidas divers specif mani encod transport most sulfurreduc enzym hydrogenas electrontransf protein were identifi which associ energi product reduc sulfur 2 two larg cluster regular interspac repeat crisprs present one which associ crenarchaealtyp cas gene superoperon none spacer sequenc yield good sequenc match known archaeal chromosom element the genom carri detect transpos integr element intein intron exclus trna gene this suggest genom structur quit stabl possibl reflect constant relat uncompetit natur environ

Kim Brügger

Lanming Chen

Markus Stark

Arne Zibat

Peter Redder

Andreas Ruepp

Mariana Awayez

Qunxin She

Roger  A. Garrett

Hans-Peter Klenk

The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 °C

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Archaea publishes original research articles as well as review articles dealing with all aspects of archaea, providing a unique venue for exchanging information about these extraordinary prokaryotes.

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Table of Contents

Table of Contents: 2007

Gene decay in archaea

The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 °C