Research Article

Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV

Table 3

Association of average number of cigarettes smoked per day (CPD) with metabolic markers among HIV-positive youth.

Outcome measure≤5 CPD
Mean (SD)
Median
>5 CPD
Mean (SD)
Median
Nonsmokers   
Mean (SD)
Median
value1

HDL cholesterol (mg/dL)60.5 (33.9)
45.0
63.1 (35.8)
50.0
68.7 (35.6)
60.0
0.18
LDL cholesterol (mg/dL)65.0 (28.1)
61.0
63.1 (29.6)
59.0
67.0 (31.6)
57.0
0.63
Non-HDL cholesterol (mg/dL)105.7 (28.6)
105.0
108.5 (26.5)
104.0
114.0 (33.1)
110.0
0.10
Triglycerides (mg/dL)97.4 (50.7)
85.0
102.5 (56.8)
92.0
98.8 (63.5)
82.0
0.87
Fasting glucose (mg/dL)88.4 (8.0)
88.0
88.9 (6.8)
88.0
88.2 (8.1)
88.0
0.84
2-hour glucose (mg/dL)85.8 (26.1)
83.5
90.3 (27.2)
87.0
93.1 (24.0)
92.0
0.10
Fasting insulin (µIU/mL)9.0 (6.5)
8.0
9.8 (8.4)
8.0
10.6 (11.3)
8.0
0.47
2-hour insulin (µIU/mL)46.9 (57.0)
29.5
38.5 (33.1)
26.0
49.8 (46.5)
39.0
0.22
hsCRP (mg/dL)2.8 (5.9)
0.9
4.3 (7.2)
1.5
3.0 (5.9)
1.0
0.25
BMI (kg/m2)24.6 (6.5)
22.9
25.5 (6.6)
23.9
25.8 (6.2)
24.1
0.37
Total body fat percent23.0 (12.6)* 
18.2
25.3 (13.7)
22.8
27.2 (13.2)
25.4
0.06
Total body fat (kg/m2)6.0 (4.7)
4.0
6.9 (5.5)
5.3
7.3 (5.0)
5.6
0.15
Trunk fat (kg/m2)2.7 (2.3)
1.8
3.3 (2.7)
2.5
3.4 (2.5)
2.5
0.13
Lower extremity fat (kg/m2)2.4 (2.0)
1.6
2.5 (2.3)
1.8
2.9 (2.1)
2.4
0.12
Total body lean (kg/m2)17.3 (2.4)
17.1
17.4 (2.7)
17.0
17.3 (2.5)
17.1
0.93

SD = standard deviation.
1 values obtained from generalized linear regression modeling (GLM).
*Significantly different compared to nonsmokers ( ).