Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels

Figure 1

The plots show HbA1c and fructosamine values from our sample. Superimposed on the graph are the lines at the threshold between normal and abnormal fructosamine values (fructosamine = 285) and normal and abnormal HbA1c values (HbA1c = 6.5). (a) plots HbA1c and fructosamine values from patients with normal albumin and hemoglobin levels defined as being in the top 3 quartiles for hemoglobin and albumin levels. Superimposed on the graph is a LOWESS curve, which is a smoothed curve showing the central tendency at each value among those with normal albumin and hemoglobin levels. Correlation between HbA1c and fructosamine = 0.72. (b) plots HbA1c and fructosamine values from patients with low hemoglobin levels (lowest quartile) and normal albumin levels. The LOWESS line is from Figure 1(a) for those with normal hemoglobin and albumin levels. Correlation between HbA1c and fructosamine = 0.63. (c) plots HbA1c and fructosamine values from patients with low albumin levels (lowest quartile) and normal hemoglobin levels. The LOWESS line is from Figure 1(a) for those with normal hemoglobin and albumin levels. Correlation between HbA1c and fructosamine = 0.75. (d) plots HbA1c and fructosamine values from all patients. The LOWESS line is from Figure 1(a) for those with normal hemoglobin and albumin levels. Correlation between HbA1c and fructosamine = 0.70.

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