Structural Differences Observed in Arboviruses of the Alphavirus and Flavivirus Genera
Figure 1
Shown in (a) is the cryo-EM reconstruction of the TC-83 strain of Venezuelan equine encephalitis virus (VEE) viewed down the strict 5-fold axis. Resolution is 4.4 Å. The trimers consist primarily of E2 with the smoother “skirt” comprised of E1. In (b) is shown a slice down the 2-fold axis. Note the transmembrane domains (arrow) and the extensive organization of the nucleocapsid (circle) compared to that seen in the flaviviruses (Figure 3(b)). With permission from Zhang et al. [22]. For full resolution images see EM DATA BANK (EMDB)/5275.
