Review Article

A Review on Platelet Activating Factor Inhibitors: Could a New Class of Potent Metal-Based Anti-Inflammatory Drugs Induce Anticancer Properties?

Table 4

IC50 data (μM) of various Ru(II)/(III) PAF inhibitors.

NumberComplexesIC50

Ru-1[Ru(bpy)2Cl2]
Ru-1a-Cl[Ru(bpy)2(L2)]Cl2
Ru-1a-PF6[Ru(bpy)2(L2)](PF6)2
Ru-1b-Cl[Ru(bpy)2(dcbpyH2)]Cl2
Ru-1b-PF6[Ru(bpy)2(dcbpyH2)](PF6)2
Ru-2[Ru(dcbpyH2)2Cl2]
Ru-2a[Ru(dcbpyH2)2(L1)](NO3)2
Ru-2b[Ru(dcbpyH2)2(L2)](NO3)2
Ru-3[Ru(bpp)Cl3]
Ru-3a[Ru(bpp)(dcbpyH)Cl]
Ru-3b[Ru(bpp)(dcbpyH2)Cl]Cl
Ru-4[Ru(bdmpp)Cl3]
Ru-4b[Ru(bdmpp)(L4)Cl](PF6)