Effects of Fruit and Vegetable Low Molecular Mass Fractions on Gene Expression in Gingival Cells Challenged with Prevotella intermedia and Actinomyces naeslundii
Figure 4
Effects of heat killed P. intermedia and A. naeslundii, and of Chicory and Mushroom LMM fractions on expression of Cyt18 (a), 4βINT (b), and HβD2 (c) in KB cells. Cells were exposed to bacteria (at the nominal bacteria: KB cell ratio of 50) and fractions (0.2x), alone and in combination, for 4 h. Gene expression was evaluated by RT-Q-PCR as described in Methods. Data, expressed as relative expression with respect to controls, represent the mean ± SD of four experiments in triplicate. Abbreviations as in legend to Figure 4. *= P ≤ 0.05: all treatment versus controls; § = P ≤ 0.05: bacteria/LMM fractions versus bacteria alone. Mann-Whitney U test.
