Loss of the NHE2 Na+/H+ Exchanger in Mice Results in Dilation of Folliculo-Stellate Cell Canaliculi
Figure 9
Nhe2-/- FS cells exhibited a reduction in the number of desmosomes associated with mitochondria. Desmosomal-mitochondrial associations can be seen in WT ((a) and (b)) and in Nhe2-/- mice (c). Desmosomes are often associated with one or two mitochondria (one from each cell). A significant decrease in desmosomal-mitochondrial associations was found in the FS cells of Nhe2-/- mice (see Table 1). Arrows point to mitochondria whose outer membranes are juxtaposed to intracellular filaments of desmosomes. Bars: 1 μm.
