Research Article

Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs

Figure 5

The population pharmacokinetic of cefuroxime lysine and cefuroxime sodium in dogs. (a): Experimental versus population-predicted plasma concentrations was generated from the population pharmacokinetic. The values for calculation were from Figure 3. The line of identity was shown; (b): Individual Weighted Residuals (IWR) of the predicted concentrations versus the predicted concentration of the antibiotic in dog plasma; (c): a comparison of the pharmacokinetic properties of predicted and experimental drug concentrations in the plasma.
507294.fig.005a
(a)
507294.fig.005b
(b)
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(c)