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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 541245, 7 pages
http://dx.doi.org/10.1155/2012/541245
Research Article

Nuclear Expression of a Mitochondrial DNA Gene: Mitochondrial Targeting of Allotopically Expressed Mutant ATP6 in Transgenic Mice

Department of Pathobiology, College of Veterinary Medicine, Auburn University, 212 Samford Hall, Auburn, AL 36849, USA

Received 10 January 2012; Revised 13 April 2012; Accepted 16 April 2012

Academic Editor: Oreste Gualillo

Copyright © 2012 David A. Dunn and Carl A. Pinkert. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • G. Jane Farrar, Naomi Chadderton, Paul F. Kenna, and Sophia Millington-Ward, “Mitochondrial disorders: aetiologies, models systems, and candidate therapies,” Trends in Genetics, 2013. View at PublisherView at Google Scholar
  • Matthew V. Cannon, Michael H. Irwin, and Carl A. Pinkert, “Mitochondrially-Imported RNA in Drug Discovery,” Drug Development Research, 2015. View at PublisherView at Google Scholar
  • Hélène Cwerman-Thibault, Sébastien Augustin, Christophe Lechauve, Jessica Ayache, Sami Ellouze, José-Alain Sahel, and Marisol Corral-Debrinski, “Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss,” Molecular Therapy — Methods & Clinical Development, vol. 2, pp. 15003, 2015. View at PublisherView at Google Scholar
  • Amutha Boominathan, Shon Vanhoozer, Nathan Basisty, Kathleen Powers, Alexandra L. Crampton, Xiaobin Wang, Natalie Friedricks, Birgit Schilling, Martin D. Brand, and Matthew S. O'Connor, “ Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant ,” Nucleic Acids Research, pp. gkw756, 2016. View at PublisherView at Google Scholar
  • Eduarda Coutinho, Cátia Batista, Fani Sousa, João Queiroz, and Diana Costa, “Mitochondrial Gene Therapy: Advances in Mitochondrial Gene Cloning, Plasmid Production, and Nanosystems Targeted to Mitochondria,” Molecular Pharmaceutics, vol. 14, no. 3, pp. 626–638, 2017. View at PublisherView at Google Scholar