BioMed Research International

Animal Models of Human Pathology 2012


Publishing date
08 Jun 2012
Status
Published
Submission deadline
09 Dec 2011

Lead Editor

1Institute of Experimental Endocrinology and Oncology, National Research Council, Naples, Italy

2NeuroEndocrine Interactions in Rheumatology and Inflammatory Diseases, Santiago University Clinical Hospital, Santiago de Compostela, Spain

3Department of Molecular Virology, Immunology & Medical Genetics, The Ohio State University, Columbus, OH, USA


Animal Models of Human Pathology 2012

Description

Based on the genetic alterations found in humans, multiple models of human pathologies have been generated in genetically engineered or drug-induced animals. These experimental models are valuable tools for understanding physiopathology of the disease and discovering novel therapeutic targets and drugs. In fact, one avenue holding tremendous potential to find therapies against human diseases is the use of intact living systems, where complex biological processes can be examined.

We invite authors to present original research articles as well as review articles that will stimulate the continuing efforts in developing animal models, ranging from invertebrates to large animals, to be used in preclinical applications, improving therapy in various fields of medicine (oncology, cardiovascular, immunology, endocrinology, brain pathologies, etc.). We are particularly interested in manuscripts that report naturally occurring, induced, or engineered animal models of human diseases and their preclinical applications. Reviews that summarize all the animal models for a particular pathology, their involvement in preclinical trials, and their future on treatment practice are also particularly welcome. Potential topics include, but are not limited to:

  • Modeling retinoblastoma in rodents
  • The use of animal models in the study of obesity
  • The value of animal models for drug development in autoimmune diseases
  • The genetics of cardiovascular disease: new insights from animal models
  • Understanding pathogenesis and therapy of ataxia telangiectasia (AT) via animal models
  • Experimental animal models of rheumatoid arthritis, lupus erythematosus, and osteoarthritis
  • Small model organisms for neurodegenerative diseases
  • Large animal models of heart failure
  • The pig: a representative animal model for humans
  • Modeling human disease using the nematode Caenorhabditis elegans
  • Drosophila models of human diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 404130
  • - Editorial

Animal Models of Human Pathology 2012

Monica Fedele | Oreste Gualillo | Andrea Vecchione
  • Special Issue
  • - Volume 2012
  • - Article ID 921617
  • - Research Article

An In Vivo Rabbit Model for the Evaluation of Antimicrobial Peripherally Inserted Central Catheter to Reduce Microbial Migration and Colonization as Compared to an Uncoated PICC

Nicholas D. Allan | Kamna Giare-Patel | Merle E. Olson
  • Special Issue
  • - Volume 2012
  • - Article ID 285938
  • - Research Article

Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy: A Microscopic Study Contrasted with the Hormonal Assays

Daniel P. Venâncio | Monica L. Andersen | ... | Marco T. De Mello
  • Special Issue
  • - Volume 2012
  • - Article ID 601786
  • - Review Article

Involvement of the Intrarenal Renin-Angiotensin System in Experimental Models of Glomerulonephritis

Maki Urushihara | Yukiko Kinoshita | ... | Shoji Kagami
  • Special Issue
  • - Volume 2012
  • - Article ID 541245
  • - Research Article

Nuclear Expression of a Mitochondrial DNA Gene: Mitochondrial Targeting of Allotopically Expressed Mutant ATP6 in Transgenic Mice

David A. Dunn | Carl A. Pinkert
  • Special Issue
  • - Volume 2012
  • - Article ID 460841
  • - Methodology Report

Development of Animal Model for Studying Deep Second-Degree Thermal Burns

Danielle dos Santos Tavares Pereira | Maria Helena Madruga Lima-Ribeiro | ... | Maria Tereza dos Santos Correia
  • Special Issue
  • - Volume 2012
  • - Article ID 817341
  • - Review Article

Think Small: Zebrafish as a Model System of Human Pathology

J. R. Goldsmith | Christian Jobin
  • Special Issue
  • - Volume 2012
  • - Article ID 346761
  • - Review Article

Advancement in the Development of Models for Hepatitis C Research

Wendy C. Carcamo | Cuong Q. Nguyen
  • Special Issue
  • - Volume 2012
  • - Article ID 692609
  • - Review Article

Animal Models of Glaucoma

Rachida A. Bouhenni | Jeffrey Dunmire | ... | Deepak P. Edward
  • Special Issue
  • - Volume 2012
  • - Article ID 201689
  • - Review Article

Cytokines and VEGF Induction in Orthodontic Movement in Animal Models

M. Di Domenico | F. D'apuzzo | ... | L. Perillo
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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