Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2013 (2013), Article ID 143028, 9 pages
http://dx.doi.org/10.1155/2013/143028
Research Article

In Vitro Culture-Induced Pluripotency of Human Spermatogonial Stem Cells

1Fertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, 606-5 Yeoksam-dong, Gangnam-gu, Seoul 135-081, Republic of Korea
2Department of Anatomy and Cell Biology, College of Medicine, Hanyang University, Seoul 133-791, Republic of Korea
3Department of Urology, CHA Bundang Medical Center, CHA University, Seongnam 463-712, Republic of Korea
4Department of Biomedical Science, College of Life Science, CHA University, Seoul 135-081, Republic of Korea

Received 27 September 2012; Accepted 29 November 2012

Academic Editor: Thomas Skutella

Copyright © 2013 Jung Jin Lim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. J. Shamblott, J. Axelman, S. Wang et al., “Derivation of pluripotent stem cells from cultured human primordial germ cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 23, pp. 13726–13731, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. C. L. Kerr, C. M. Hill, P. D. Blumenthal, and J. D. Gearhart, “Expression of pluripotent stem cell markers in the human fetal testis,” Stem Cells, vol. 26, no. 2, pp. 412–421, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Kanatsu-Shinohara, K. Inoue, J. Lee et al., “Generation of pluripotent stem cells from neonatal mouse testis,” Cell, vol. 119, no. 7, pp. 1001–1012, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Guan, K. Nayernia, L. S. Maier et al., “Pluripotency of spermatogonial stem cells from adult mouse testis,” Nature, vol. 440, no. 7088, pp. 1199–1203, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Seandel, D. James, S. V. Shmelkov et al., “Generation of functional multipotent adult stem cells from GPR125+ germline progenitors,” Nature, vol. 449, no. 7160, pp. 346–350, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Conrad, M. Renninger, J. Hennenlotter et al., “Generation of pluripotent stem cells from adult human testis,” Nature, vol. 456, no. 7220, pp. 344–349, 2008. View at Publisher · View at Google Scholar
  7. N. Kossack, J. Meneses, S. Shefi et al., “Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells,” Stem Cells, vol. 27, no. 1, pp. 138–149, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. N. Golestaneh, M. Kokkinaki, D. Pant et al., “Pluripotent stem cells derived from adult human testes,” Stem Cells and Development, vol. 18, no. 8, pp. 1115–1125, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. S. C. Mizrak, J. V. Chikhovskaya, H. Sadri-Ardekani et al., “Embryonic stem cell-like cells derived from adult human testis,” Human Reproduction, vol. 25, no. 1, pp. 158–167, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. J. V. Chikhovskaya, M. J. Jonker, A. Meissner, T. M. Breit, S. Repping, and A. M. van Pelt, “Human testis-derived embryonic stem cell-like cells are not pluripotent, but possess potential of mesenchymal progenitors,” Human Reproduction, vol. 27, no. 1, pp. 210–221, 2012. View at Google Scholar
  11. K. Takahashi, K. Tanabe, M. Ohnuki et al., “Induction of pluripotent stem cells from adult human fibroblasts by defined factors,” Cell, vol. 131, no. 5, pp. 861–872, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Tapia, M. J. Araúzo-Bravo, K. Ko, and H. R. Schöler, “Concise review: challenging the pluripotency of human testis-derived ESC-like cells,” Stem Cells, vol. 29, no. 8, pp. 1165–1169, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Ko, M. J. Araúzo-Bravo, N. Tapia et al., “Human adult germline stem cells in question,” Nature, vol. 465, no. 7301, pp. E1–E2, 2010. View at Publisher · View at Google Scholar
  14. J. J. Lim, S. Y. Sung, H. J. Kim et al., “Long-term proliferation and characterization of human spermatogonial stem cells obtained from obstructive and non-obstructive azoospermia under exogenous feeder-free culture conditions,” Cell Proliferation, vol. 43, no. 4, pp. 405–417, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. M. G. A. Nagy K and K. Vinetrstein, Isolation and Culture of Blastocyst-Derived Stem Cell Lines. Manipulating the Mouse Embryo, Cold Spring Harbor Laboratory Press, Harbor, NY, USA, third edition, 2001.
  16. Y. Yan, J. Yang, W. Bian, and N. Jing, “Mouse nestin protein localizes in growth cones of P19 neurons and cerebellar granule cells,” Neuroscience Letters, vol. 302, no. 2-3, pp. 89–92, 2001. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Araki, H. Ueda, and S. Fujimoto, “Immunocytochemical localization of alpha-fetoprotein in the developing and carbon tetrachloride-treated rat liver,” Acta Anatomica, vol. 143, no. 3, pp. 169–177, 1992. View at Google Scholar · View at Scopus
  18. M. Stimpfel, T. Skutella, M. Kubista, E. Malicev, S. Conrad, and I. Virant-Klun, “Potential stemness of frozen-thawed testicular biopsies without sperm in infertile men included into the in vitro fertilization programme,” Journal of Biomedicine and Biotechnology, vol. 2012, Article ID 291038, 15 pages, 2012. View at Publisher · View at Google Scholar
  19. M. Kanatsu-Shinohara, N. Ogonuki, K. Inoue et al., “Long-term proliferation in culture and germline transmission of mouse male germline stem cells,” Biology of Reproduction, vol. 69, no. 2, pp. 612–616, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Kanatsu-Shinohara, N. Ogonuki, T. Iwano et al., “Genetic and epigenetic properties of mouse male germline stem cells during long-term culture,” Development, vol. 132, no. 18, pp. 4155–4163, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. F. K. Hamra, K. M. Chapman, D. M. Nguyen et al., “Self renewal, expansion, and transfection of rat spermatogonial stem cells in culture,” PNAS, vol. 102, pp. 17430–17435, 2005. View at Google Scholar
  22. B. Y. Ryu, H. Kubota, M. R. Avarbock, and R. L. Brinster, “Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 40, pp. 14302–14307, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. M. F. Pera, B. Reubinoff, and A. Trounson, “Human embryonic stem cells,” Journal of Cell Science, vol. 113, no. 1, pp. 5–10, 2000. View at Google Scholar · View at Scopus
  24. H. J. Kim, H. J. Lee, J. J. Lim et al., “Identification of an intermediate state as spermatogonial stem cells reprogram to multipotent cells,” Molecules and Cells, vol. 29, no. 5, pp. 519–526, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. C. L. Kerr, C. M. Hill, P. D. Blumenthal, and J. D. Gearhart, “Expression of pluripotent stem cell markers in the human fetal testis,” Stem Cells, vol. 26, no. 2, pp. 412–421, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. Y. Q. Shi, Q. Z. Wang, S. Y. Liao, Y. Zhang, Y. X. Liu, and C. S. Han, “In vitro propagation of spermatogonial stem cells from KM mice,” Frontiers in Bioscience, vol. 11, no. 2, pp. 2614–2622, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. M. C. Hofmann, L. Braydich-Stolle, and M. Dym, “Isolation of male germ-line stem cells; Influence of GDNF,” Developmental Biology, vol. 279, no. 1, pp. 114–124, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Schuldiner, O. Yanuka, J. Itskovitz-Eldor, D. A. Melton, and N. Benvenisty, “Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 21, pp. 11307–11312, 2000. View at Google Scholar · View at Scopus
  29. M. Stojkovic, M. Lako, T. Strachan, and A. Murdoch, “Derivation, growth and applications of human embryonic stem cells,” Reproduction, vol. 128, no. 3, pp. 259–267, 2004. View at Publisher · View at Google Scholar · View at Scopus