BioMed Research International

Stem Cells in Reproductive Tissues: From the Basics to Clinics


Publishing date
15 Feb 2013
Status
Published
Submission deadline
28 Sep 2012

1Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Slajmerjeva 3, 1000 Ljubljana, Slovenia

2Institute for Anatomy and Cell Biology, Medical Faculty of Heidelberg, Heidelberg University, Im Neuenheimer Feld 307, 69120 Heidelberg, Germany

3Department of Stem Cell Biology, National Institute for Research in Reproductive Health, JM Street, Parel, Mumbai 400012, India

4Center for Assisted Reproduction, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China


Stem Cells in Reproductive Tissues: From the Basics to Clinics

Description

Currently, there is steadily increasing experimental evidence on the existence of pluripotent/multipotent stem cells in neonatal and adult mammalian ovaries, including humans. The ovarian stem cells seem to be present in the ovarian surface epithelium layer, in the ovarian cortex tissue, or as a subpopulation of granulosa cells in adult human ovaries. Recently, more articles have reported the presence of stem cell populations in the adult tissues of human endometrium and oviducts. The testicular tissues might be an important source of stem cells, from the in vitro proliferating and reprogrammed spermatogonia to the mesenchymal stem cells expressing some markers of pluripotency. The new approach–understanding of stem cells in reproductive tissues–is of enormous value in terms of gaining a better understanding of some gynecological diseases (e.g., premature ovarian failure and endometriosis), the manifestation of aggressive cancers, a potential gamete renewal, and potential use of reproductive tissues that are commonly thrown away in medical practice as an important source of stem cells for regenerative medicine. The new knowledge on stem cells in reproductive tissues might lead to better diagnostics and more advanced and individualized therapies of different diseases in the future.

The main focus of this special issue will be on the new and established findings with a goal to better understand some new aspects of stem cells in gonadal and other reproductive tissues in the animal models and in humans. The special issue will become an important international forum for researchers and have tendency to summarize the most recent and advanced developments, approaches, and ideas in the field. Potential topics include, but are not limited to:

  • Stem cells in fetal and adult ovaries
  • Stem cells in fetal and adult testicles
  • Spermatogonial stem cells
  • Endometrial stem cells
  • Stem cells in menstrual blood
  • Stem cells in oviducts
  • Primordial germ cells
  • Cancer stem cells
  • Stem cell basics
  • Stem cell research, diagnostics, and treatment
  • In vitro gametogenesis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 357102
  • - Editorial

Stem Cells in Reproductive Tissues: From the Basics to Clinics

Irma Virant-Klun | Thomas Skutella | ... | Xuan Jin
  • Special Issue
  • - Volume 2013
  • - Article ID 901821
  • - Research Article

Isolation, Characterization, and Transduction of Endometrial Decidual Tissue Multipotent Mesenchymal Stromal/Stem Cells from Menstrual Blood

Filippo Rossignoli | Anna Caselli | ... | Massimo Dominici
  • Special Issue
  • - Volume 2013
  • - Article ID 243649
  • - Research Article

HTR8/SVneo Cells Display Trophoblast Progenitor Cell-Like Characteristics Indicative of Self-Renewal, Repopulation Activity, and Expression of “Stemness-” Associated Transcription Factors

Maja Weber | Ilka Knoefler | ... | Justine S. Fitzgerald
  • Special Issue
  • - Volume 2013
  • - Article ID 861460
  • - Research Article

Expression of Pluripotency and Oocyte-Related Genes in Single Putative Stem Cells from Human Adult Ovarian Surface Epithelium Cultured In Vitro in the Presence of Follicular Fluid

Irma Virant-Klun | Thomas Skutella | ... | Helena Meden-Vrtovec
  • Special Issue
  • - Volume 2013
  • - Article ID 879489
  • - Review Article

Gene Expression Profiling of Human Oocytes Developed and Matured In Vivo or In Vitro

Irma Virant-Klun | Katja Knez | ... | Thomas Skutella
  • Special Issue
  • - Volume 2013
  • - Article ID 529589
  • - Research Article

Recovery of Fertility in Azoospermia Rats after Injection of Adipose-Tissue-Derived Mesenchymal Stem Cells: The Sperm Generation

Cihangir Cakici | Bugra Buyrukcu | ... | Erdal Karaoz
  • Special Issue
  • - Volume 2013
  • - Article ID 682326
  • - Review Article

Very Small Embryonic-Like Stem Cells: Implications in Reproductive Biology

Deepa Bhartiya | Sreepoorna Unni | ... | Sandhya Anand
  • Special Issue
  • - Volume 2013
  • - Article ID 150901
  • - Review Article

Use of Insulin to Increase Epiblast Cell Number: Towards a New Approach for Improving ESC Isolation from Human Embryos

Jared M. Campbell | Michelle Lane | ... | Mark B. Nottle
  • Special Issue
  • - Volume 2013
  • - Article ID 807863
  • - Research Article

In Vitro Large Scale Production of Human Mature Red Blood Cells from Hematopoietic Stem Cells by Coculturing with Human Fetal Liver Stromal Cells

Jiafei Xi | Yanhua Li | ... | Xuetao Pei
  • Special Issue
  • - Volume 2013
  • - Article ID 916819
  • - Review Article

Ovarian Cancer Stem Cells: A New Target for Cancer Therapy

Qinglei Zhan | Chunmei Wang | Saiming Ngai
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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