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BioMed Research International
Volume 2013, Article ID 161329, 4 pages
Research Article

Fish Tank Granuloma Caused by Mycobacterium marinum in Two Aquarists: Two Case Reports

1Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
2Department of Clinical Microbiology and Parasitology, County Hospital Pribram, 261 95 Pribram, Czech Republic
3Department of Dermatovenerology, General University Hospital and 1st Faculty of Medicine Charles University, 128 21 Prague, Czech Republic

Received 10 October 2013; Accepted 19 November 2013

Academic Editor: Tomasz Jagielski

Copyright © 2013 Michal Slany et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Mycobacterium marinum, the cause of chronic systemic infections in fish, occasionally causes granulomatous skin and soft tissue lesions in humans. Cutaneous mycobacterial infection in two patients owing to unusual circumstances is presented in this report. The first patient was infected through improper hygienic behavior, while infection in the second patient was previously misdiagnosed as rheumatoid arthritis and treated with methylprednisolone for a period of three months, which resulted in a rare systemic spread of M. marinum into the bones of the hand, testis, and epididymis. Simultaneously, screening for possible sources of M. marinum infection in patients' aquaria revealed positive fish harboring VNTR profiles identical to those obtained for clinical isolates from patients.