BioMed Research International

Recent Developments in Mycobacteriology: A Clinical and Diagnostic Perspective


Publishing date
28 Feb 2014
Status
Published
Submission deadline
11 Oct 2013

1Department of Applied Microbiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland

2Department of Medical Microbiology, Radboud University, GLD Nijmegen, The Netherlands

3WHO Supranational Tuberculosis Reference Laboratory, Tuberculosis & Mycobacteria Unit, Institut Pasteur de la Guadeloupe, Abymes, Guadeloupe, France

4Mycobacterium Genetics and Physiology Unit, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland


Recent Developments in Mycobacteriology: A Clinical and Diagnostic Perspective

Description

The genus Mycobacterium Mycobacterium accommodates more than 150 species and splits into three major groups, that is, M. tuberculosis complex (MTBC), M. leprae, and mycobacteria other than MTBC and M. leprae, collectively referred to as nontuberculous mycobacteria (NTM). The most famous member of the MTBC is Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), which, with over 8 million new cases and nearly 2 million deaths per annum, continues to cause one of the major health burdens for human population. Whereas the prevalence of TB has been closely monitored in most parts of the world, the epidemiology of NTM infections remains poorly defined, in spite of the fact that the importance of NTMs as a cause of opportunistic infections has been increasingly recognized over the last two decades in humans. Finally leprosy, whose causative agent is M. leprae, although uncommon in nontropical regions, still persists in some endemic regions, mainly in Asia and Africa, affecting a quarter million of people every year.

The main purpose of this special issue is to summarize the most recent achievements in mycobacteriology, with particular emphasis on the developments which have direct relevance to the clinical practice and diagnostic performance. Potential topics include, but are not limited to:

  • TB and NTM infections: Epidemiology and clinical perspective
  • Atypical presentations of mycobacterial infections
  • Leprosy: Current insights
  • Mechanisms involved in host-pathogen interactions
  • Immunology and pathogenesis
  • Advances in diagnostic techniques
  • Drug regimens and treatment outcomes
  • Studies on drug resistance
  • New antimycobacterial agents
  • Progress in anti-TB vaccine development
  • Genetic markers, genotyping, and next generation sequencing
  • Phylogeny and evolution of mycobacteria

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/microbiology/rdm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 813185
  • - Editorial

Recent Developments in Mycobacteriology: A Clinical and Diagnostic Perspective

Tomasz Jagielski | Jakko van Ingen | ... | Jarosław Dziadek
  • Special Issue
  • - Volume 2014
  • - Article ID 367268
  • - Research Article

The Structural Modeling of the Interaction between Levofloxacin and the Mycobacterium tuberculosis Gyrase Catalytic Site Sheds Light on the Mechanisms of Fluoroquinolones Resistant Tuberculosis in Colombian Clinical Isolates

N. Alvarez | E. Zapata | ... | J. Robledo
  • Special Issue
  • - Volume 2014
  • - Article ID 398484
  • - Research Article

Predicting Mycobacterium tuberculosis Complex Clades Using Knowledge-Based Bayesian Networks

Minoo Aminian | David Couvin | ... | Kristin P. Bennett
  • Special Issue
  • - Volume 2014
  • - Article ID 418563
  • - Research Article

Experimental Inoculation of BFDV-Positive Budgerigars (Melopsittacus undulatus) with Two Mycobacterium avium subsp. avium Isolates

Aleksandra Ledwoń | Rafał Sapierzyński | ... | Marcin Kozak
  • Special Issue
  • - Volume 2014
  • - Article ID 782071
  • - Research Article

Comparison of Ligation-Mediated PCR Methods in Differentiation of Mycobacterium tuberculosis Strains

Anna Zaczek | Anna Brzostek | ... | Jaroslaw Dziadek
  • Special Issue
  • - Volume 2014
  • - Article ID 715841
  • - Research Article

Mycobacterium avium Subsp. avium Infection in Four Veal Calves: Differentiation from Intestinal Tuberculosis

Christine Goepfert | Nadine Regenscheit | ... | Horst Posthaus
  • Special Issue
  • - Volume 2014
  • - Article ID 398108
  • - Research Article

Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories

Diana Machado | Jorge Ramos | ... | Miguel Viveiros
  • Special Issue
  • - Volume 2014
  • - Article ID 951978
  • - Research Article

Assessment of Mycobacterium bovis Deleted in p27-p55 Virulence Operon as Candidate Vaccine against Tuberculosis in Animal Models

María V. Bianco | Simon Clark | ... | Fabiana Bigi
  • Special Issue
  • - Volume 2014
  • - Article ID 645802
  • - Review Article

Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria

Tomasz Jagielski | Jakko van Ingen | ... | Jacek Bielecki
  • Special Issue
  • - Volume 2013
  • - Article ID 178725
  • - Research Article

Short Communication: Subtyping of Mycobacterium kansasii by PCR-Restriction Enzyme Analysis of the hsp65 Gene

Zofia Bakuła | Aleksandra Safianowska | ... | Tomasz Jagielski
BioMed Research International
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