Selected DEG in DKD for FVA analysis.
|Gene symbol||Entrez gene ID||FC (glomeruli)||FC (tubuli)||Reaction||Gene name|
|LPL||4023||−9.18501||−4.38411||LPS; LPS2||Lipoprotein lipase|
|GCNT3||9245||2.12739||1.847147||CORE4GTg||Glucosaminyl (N-acetyl) transferase 3|
|Ribonucleotidereductase M2 polypeptide|
|B3GNT1||10678||−2.28274||−1.53357||B3GNT11g||UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1|
|Note: These DEG were selected from a previous study , and their flux spans of metabolic reactions were detected to fluctuate markedly (Figure 5). It suggests the essential role of these genes in DKD process. Knocking out of these genes may cause metabolism alterations and affect the emergence of DKD. The first column is the gene symbol of DEG; the second column is the Entrez gene ID; the third and fourth columns are the fold change value for glomeruli and tubuli cell, respectively; the fifth column shows the representative affected reactions, and the sixth column is gene name.|